Start with your ICP. Outbound AI SDRs perform dramatically better on a narrow, well-defined Ideal Customer Profile. Signal-based tools like Spear only shine when the ICP is tight enough that signals matter.
Decide on autonomy. Fully autonomous agents (11x, Artisan, Salesforge) reduce operational overhead but require trust and governance. Copilot-style tools (Regie.ai, Amplemarket) keep humans in the loop and integrate better with existing SEP workflows.
Own or bring your own inboxes. Vendors that ship with owned inboxes and warmup (Artisan, Salesforge) protect your domain reputation. Bringing your own is cheaper but requires deliverability discipline.
Model true cost. Custom-priced tools like 11x and Artisan typically land between $30k and $150k/year. Flat-priced tools (AiSDR, Jason AI) are more predictable but cap at lower volumes.